Friday, July 17, 2009

Ans

Dispensing Form

Name of Patient: Wu Ming Wing

1. Name of product: Doxycap

2. Content: Doxycycline 100mg

3. Pharmacological / Chemical Classification:
Antibiotic- Tetracycline

Poison Schedule: POM

4. Indication:
Treatment of Acne

5. Patient Details: Adult

Weight = Nil

6. Prescription Directions:
1 capsule to be taken in the morning for one month

7. Dose Considerations / Dose Calculations:
1 capsule once a day x 1 month = 1x 1 x 30 = 30 capsules


8. Expiry Date: N.A.

9. Drug Interactions:
• Absorption impaired by antacids & iron prepration

10. Side Effects:
• Nausea, vomiting, diarrhoea, glossitis, stomatitis, proctitis. Blood disorders.

11. Contraindications / Precautions:
• Take tab in upright position w/ adequate fluids.
• Causes photosensitivity (discontinue use).
• Causes increased intracranial pressure in infant.

12. Storage / Packaging Instructions:
Store in a cool, dry place.


14. Patient Counselling
• This an antibiotic for your acne treatment
• Take one capsule once a day for one month
• Should be taken with food
• (Take w/ full glass of water & remain upright for at least 1/2 hr.
• Avoid taking w/dairy products.)
• It may cause photosensitivity, so use sun block when you go out
• If you experience any hypersensitivities reaction, such as rashes or puffy eye or dry lips. Stop the medication
(5 marks)



















Dispensing Form

Name of Patient: Wu Ming Wing

1. Name of product: Differin Gel 30g

2. Content: Adapalene

3. Pharmacological / Chemical Classification:
Acne Treatment preparation

Poison Schedule: POM

4. Indication:
Acne vulgaris where comedones, papules & pustules predominate. Acne of the face, chest or back.

5. Patient Details: Adult

Weight = Nil

6. Prescription Directions:
Apply to the affected area before bedtime after washing

7. Dose Considerations / Dose Calculations:
1 tube= 30g


8. Expiry Date: N.A.

9. Drug Interactions:
• Minimal

10. Side Effects:
• Erythema, scaling, dryness, pruritus & burning.

11. Contraindications / Precautions:
• Avoid contact w/ eyes, lips, angles of the nose & mucous membranes.
• Do not apply to cuts, abrasions, eczematous skin, and severe acne.
• Minimise exposure to excessive sunlight, including sunlamps.

12. Storage / Packaging Instructions:
Store in a cool, dry place.

14. Patient Counselling
• This a gel for your acne treatment
• Apply to the affect area at night before bedtime after washing
• You may experience a little bit of peeling effect
• Your skin will tend to a bit dry
• Avoid contact w/ eyes, lips, angles of the nose & mucous membranes.
• Do not apply to cuts, abrasions, eczematous skin, severe acne.
• Minimise exposure to excessive sunlight, including sunlamps.
• Use Sunscreen in the morning everyday
(5 marks)

Dispensing Form

Name of Patient: Wu Ming Wing

1. Name of product: Dalacin 1 % Lotion

2. Content: Clindamycin 1 %

3. Pharmacological / Chemical Classification:
Antibiotic-acne treatment preparation

Poison Schedule: POM

4. Indication:
Acne vulgaris

5. Patient Details: Adult

Weight = Nil

6. Prescription Directions:
Apply to the affected area two times a day

7. Dose Considerations / Dose Calculations:
1 tube= 30ml


8. Expiry Date: N.A.

9. Drug Interactions:
• Antagonism w/ erythromycin.

10. Side Effects:
• Skin irritation & dryness,
• Abdominal pain, GI disturbances,
• Contact dermatitis, stinging of the eye, gm-ve folliculitis, skin oiliness.

11. Contraindications / Precautions:
• History of hypersensitivity to clindamycin or lincomycin;
• regional enteritis; ulcerative colitis, antibiotic-related colitis.
12. Storage / Packaging Instructions:
Store in a cool, dry place.

14. Patient Counselling
• This is a antibiotic lotion for your acne treatment
• Apply to the affect area two times a day
• Store in cool dry place








Case Study 2: Patient Presentation (25 marks)

A secondary school girl come to your pharmacy asking you some preparation for pimple treatment. She had some close comedone in her forehead and 4 minor outbreak at the T zone area. Her friend recommended her this brand called PanOxy. After looking through the counter, she found that there are three types, namely, 2.5, 5 and 10. She is asking you which one is suitable for her. Besides, she wanted you to recommend her a antibacterial facial wash.

1. What is the active ingredient in PanOxy and what is the different in the three types of PanOxy?
• Active ingredient is Benzyl peroxide
• The different number represent different percentage of the benzyl peroxide
• 2.5= 2.5%, 5 = 5%, 10=10%


2. What others alternative which contain the same ingredient besides PanOxy?

• Cream
i. Oxy, Papulex oil free cream, Brevoxyl
• Gel
i. Benzac AC

3. What is the different between different Dosage Form?

• Gel
i. Faster absorption due to water base
ii. Stronger compare to the similar strength of cream

• Cream
i. Easier to administer due to the texture
ii. Tinted color for coverage

4. What type of antibacterial face wash that you can recommend to her?
(3 marks)
• Triclosan
i. Oxy facial wash

• Tea Tree
i. Thursday plantation facial wash

• Chlorhexidine and Cetrimide
i. Acnederm Medicated Foaming Wash

• Montaline C40
i. Sebamed Clear Face Antibacterial Cleaning Foam
5. Besides Benzyl Perioxide, what other chemical can be used in the treatment of pimple? And how they work?

• Salicylic acid.
i. This ingredient slows shedding of cells inside the hair follicles, which prevents the pores from clogging. It may also break down whiteheads (clogged pores that have no opening) and blackheads (pores that are open and have a dark surface). Salicylic acid can cause mild stinging and skin irritation. OTC acne products are available with 0.5 percent to 2 percent salicylic acid.
ii. E.g.,
• Sulfur and resorcinol.
iRarely used alone, sulfur and resorcinol are often found together in acne products. These ingredients remove dead skin cells that clog pores and help remove excess oil. They may also break down whiteheads and blackheads. Sulfur and resorcinol can cause redness and peeling, which may occur several days after using the product.
ii. E.g., Acne Clear, Acne Aid
• Alcohol and acetone.
i. Often available in astringents and other cleansing washes, alcohol and acetone remove dirt and oils from the skin. Acne products that contain these ingredients can cause a mild burning or stinging sensation
ii. E.g., Skinoren
• Zinc Oxide
i. Mild antiseptic and reduce inflammation and rashes

6. What are the other advice can you give her when she is using acne treatment product?

•Avoid oily cosmetics, sunscreens and hair products. Instead use products labeled "oil-free" or "noncomedogenic," which means they won't clog pores.
•Wash problem areas twice daily with a non medicated soap or mild cleanser. But don't overdo it. Excessive washing and scrubbing can worsen acne.
•Apply just enough acne product to cover the problem areas.
•Use an oil-free, water-based moisturizer to help alleviate dry, peeling skin.
•Don't pick or squeeze blemishes. Infection or scarring may result.

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